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How long does it take to stop smoking on Wellbutrin? You begin taking bupropion daily, 1 to 2 weeks before you quit smoking. This builds up the level of medicine in your body. You take bupropion for 7 to 12 weeks after you stop using tobacco. You can take it for as long as 6 months to a year.
Does smoking affect antipsychotics? Cigarette smoke also increases the activity of CYP 1A2 enzymes, thus decreasing the concentration of many drugs, including clozapine and olanzapine. Conversely, upon smoking cessation, smokers may require a reduction in the dosage of antipsychotics.
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