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SARS-Coronavirus-2 (SARS-CoV-2) causes Coronavirus illness 2019 (COVID-19), an infectious respiratory disease causing hundreds of deaths and overwhelming public well being systems.Similar human studies have not yet been carried out, as the principle trials are geared toward assessing primarily vaccine safety and immunogenicity.In particular, we discuss structural insights into the SARS-CoV-2 spike protein, a major determinant of transmissibility, and discuss key molecular elements that can assist in understanding and fighting this new global menace.SARS-CoV-2 vaccines would possibly come too late to affect the primary wave of this pandemic, however they could be useful if further subsequent waves happen or in a publish-pandemic perspective during which the virus continues to circulate as a seasonal virus.

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